Models / Mistral Medium 3.5 128B
Can I run Mistral Medium 3.5 128B locally?
Mistral AI · 128B parameters · dense · up to 256K context · license other · Hugging Face
At Q4_K_M with a 32K context, Mistral Medium 3.5 128B needs about 93.3 GB of GPU or unified memory by our estimate. The official checkpoint (FP8) is 267 GB on disk.
Memory by quantization and context
| Quantization | Weights | Total at 8K | Total at 32K | Total at 128K |
|---|---|---|---|---|
| Q3_K_M (~4.0 bit) | 63.8 GB | 69.7 GB | 78.5 GB | 114 GB |
| Q4_K_M (~4.9 bit, popular default) | 78.1 GB | 84.4 GB | 93.3 GB | 129 GB |
| Q5_K_M (~5.7 bit) | 91.0 GB | 97.7 GB | 107 GB | 142 GB |
| Q6_K (~6.6 bit) | 105 GB | 112 GB | 121 GB | 156 GB |
| Q8_0 (~8.5 bit, near-lossless) | 136 GB | 144 GB | 153 GB | 188 GB |
| F16 / BF16 (16 bit) | 255 GB | 267 GB | 276 GB | 311 GB |
Bits per weight from llama.cpp's quantize docs. F16 KV cache. Totals include our runtime-overhead estimate.
Cheapest hardware that fits (Q4_K_M, 32K)
- 4× NVIDIA Tesla V100 32GB (PCIe or SXM2): about €2,484 (used, ebay.co.uk, 124 GB usable)
- Framework Desktop (Ryzen AI Max+ 395, 128GB): about €2,875 (used, ebay.co.uk, 120 GB usable)
- GMKtec EVO-X2 (Ryzen AI Max+ 395, 128GB): about €3,175 (new, newegg.com, 120 GB usable)
- ASUS Ascent GX10 (GB10, 128GB): about €4,136 (new, alternate.de, 120 GB usable)
- 4× AMD Instinct MI100 32GB: about €4,521 (used, ebay.co.uk, 124 GB usable)
Runs in
| Tool | Platforms | How | Source |
|---|---|---|---|
| Ollama Desktop app + CLI | macOS, Windows, Linux | ollama run mistral-medium-3.5:128b | source |
| llama.cpp Inference engine (C/C++) | Linux, Windows, macOS, Android (build) | GGUF: bartowski/mistralai_Mistral-Medium-3.5-128B-GGUF | source |
| MLX (mlx-lm) Apple framework + CLI | macOS (Apple Silicon only) | MLX conversion: mlx-community/Mistral-Medium-3.5-128B-4bit | source |
| vLLM Serving engine | Linux | named in the official model card | source |
| SGLang Serving engine | Linux | named in the official model card | source |
Only tools with a public source are listed: an official build (ggml-org, lmstudio-community, mlx-community, bartowski or Unsloth on Hugging Face), the model card, ollama.com or the tool's own README. Apps built on llama.cpp, such as Jan and PocketPal AI, can usually load the same GGUF files. All local apps.
Try other settings
21 hardware options fit
Cheapest real offer per device from AI Hardware Deals, converted to EUR at approximate rates. Multi-GPU rows multiply the card price.
| Setup | Headroom | ||||
|---|---|---|---|---|---|
| Framework Desktop (Ryzen AI Max+ 395, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €2,875 used, ebay.co.uk | ≤ 3 tok/s |
| GMKtec EVO-X2 (Ryzen AI Max+ 395, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €3,175 new, newegg.com | ≤ 3 tok/s |
| ASUS Ascent GX10 (GB10, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €4,136 new, alternate.de | ≤ 3 tok/s |
| HP Z2 Mini G1a (Ryzen AI Max+ PRO 395, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €5,686 new, mindfactory.de | ≤ 3 tok/s |
| Lenovo ThinkStation PGX (GB10, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €5,829 new, karley.de | ≤ 3 tok/s |
| Apple Mac Studio M4 Max 128GB (2025) unified memory | 1 device | 96.0 GB | 2.7 GB | €5,979 used, ebay.co.uk | ≤ 7 tok/s |
| Apple Mac Studio M5 Max 128GB (2026) unified memory | 1 device | 96.0 GB | 2.7 GB | €6,189 new, macconsultshop.de | ≤ 8 tok/s |
| Dell Pro Max with GB10 (FCM1253, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €6,663 new, eurieka.ie, excl. VAT | ≤ 3 tok/s |
| Apple Mac Studio M3 Ultra 256GB (2025) unified memory | 1 device | 192 GB | 98.7 GB | €6,724 used, apple.com | ≤ 10 tok/s |
| Gigabyte AI TOP ATOM (GB10, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €6,795 new, grafikkarten.com | ≤ 3 tok/s |
| NVIDIA DGX Spark (GB10, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €6,999 new, grafikkarten.com | ≤ 3 tok/s |
| HP ZGX Nano G1n AI Station (GB10, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €7,127 new, office-partner.de | ≤ 3 tok/s |
| MSI EdgeXpert MS-C931 (GB10, 128GB) unified memory | 1 device | 120 GB | 26.7 GB | €7,308 new, buyzero.de | ≤ 3 tok/s |
| NVIDIA A40 48GB server GPU (passive cooling) | 2× cards | 94.0 GB | 0.7 GB | €8,509 used, ebay.co.uk | n/a |
| NVIDIA RTX A6000 48GB workstation GPU | 2× cards | 94.0 GB | 0.7 GB | €8,698 used, ebay.ca | n/a |
| Apple Mac Studio M5 Ultra 256GB (2026) unified memory | 1 device | 192 GB | 98.7 GB | €9,830 new, abt.com | ≤ 15 tok/s |
| NVIDIA RTX 6000 Ada 48GB workstation GPU | 2× cards | 94.0 GB | 0.7 GB | €18,786 new, jacob.de | n/a |
| NVIDIA A100 80GB PCIe server GPU (passive cooling) | 2× cards | 158 GB | 64.7 GB | €29,998 used, ebay.nl | n/a |
| NVIDIA DGX Station (GB300) unified memory | 1 device | 740 GB | 647 GB | €83,738 new, configurator.exxactcorp.com | ≤ 91 tok/s |
| AMD Radeon Pro W7900 48GB workstation GPU | 2× cards | 94.0 GB | 0.7 GB | no verified price | n/a |
| Apple Mac Studio M5 Ultra 512GB (2026) unified memory | 1 device | 384 GB | 291 GB | no verified price | ≤ 15 tok/s |
Speed ceiling is memory bandwidth divided by the bytes of (active) weights read per token, shown only where we have a sourced bandwidth figure. Real decode speed is lower, especially with long contexts or when splitting across cards. All memory numbers are estimates; see the methodology.
FAQ
- How much VRAM does Mistral Medium 3.5 128B need?
- About 93.3 GB at Q4_K_M with a 32K-token context (78.1 GB weights, 11.8 GB KV cache, 3.3 GB overhead). These are estimates.
- Can I run Mistral Medium 3.5 128B on a single GPU?
- Not at Q4_K_M with 32K context on any single GPU in our catalog. Use several GPUs, a high-memory unified-memory machine, a smaller quantization or a shorter context.
- Which apps can run Mistral Medium 3.5 128B locally?
- Verified so far: Ollama, llama.cpp, MLX (mlx-lm), vLLM, SGLang. Each entry links to its source on this page.