Can I Run This LLM?

Models / Qwen3.5 122B-A10B

Can I run Qwen3.5 122B-A10B locally?

Qwen · 125B parameters · mixture of experts, 10B active per token · up to 256K context · license apache-2.0 · Hugging Face

At Q4_K_M with a 32K context, Qwen3.5 122B-A10B needs about 80.6 GB of GPU or unified memory by our estimate. The official checkpoint is 250 GB on disk.

Hybrid model: only the full-attention layers keep a growing KV cache; linear/conv layers keep a small fixed state (not counted).

Memory by quantization and context

QuantizationWeightsTotal at 8KTotal at 32KTotal at 128K
Q3_K_M (~4.0 bit)62.5 GB65.6 GB66.2 GB68.6 GB
Q4_K_M (~4.9 bit, popular default)76.5 GB80.0 GB80.6 GB83.0 GB
Q5_K_M (~5.7 bit)89.2 GB93.1 GB93.7 GB96.1 GB
Q6_K (~6.6 bit)103 GB107 GB108 GB110 GB
Q8_0 (~8.5 bit, near-lossless)133 GB138 GB139 GB141 GB
F16 / BF16 (16 bit)250 GB259 GB259 GB262 GB

Bits per weight from llama.cpp's quantize docs. F16 KV cache. Totals include our runtime-overhead estimate.

Cheapest hardware that fits (Q4_K_M, 32K)

  1. 3× NVIDIA Tesla V100 32GB (PCIe or SXM2): about €1,863 (used, ebay.co.uk, 93.0 GB usable)
  2. Framework Desktop (Ryzen AI Max+ 395, 128GB): about €2,875 (used, ebay.co.uk, 120 GB usable)
  3. GMKtec EVO-X2 (Ryzen AI Max+ 395, 128GB): about €3,175 (new, newegg.com, 120 GB usable)
  4. 3× AMD Instinct MI100 32GB: about €3,390 (used, ebay.co.uk, 93.0 GB usable)
  5. 4× Intel Arc Pro B60 24GB: about €3,596 (new, mindfactory.de, 92.0 GB usable)

Runs in

ToolPlatformsHowSource
Ollama
Desktop app + CLI
macOS, Windows, Linuxollama run qwen3.5:122b-a10bsource
LM Studio
Desktop app
macOS, Windows (x64, arm64), Linux (x64, arm64)lmstudio-community build: lmstudio-community/Qwen3.5-122B-A10B-GGUFsource
llama.cpp
Inference engine (C/C++)
Linux, Windows, macOS, Android (build)GGUF: bartowski/Qwen_Qwen3.5-122B-A10B-GGUFsource
MLX (mlx-lm)
Apple framework + CLI
macOS (Apple Silicon only)MLX conversion: mlx-community/Qwen3.5-122B-A10B-4bitsource
KTransformers
CPU+GPU hybrid engine
Linux, Windowsnamed in the official model cardsource
vLLM
Serving engine
Linuxnamed in the official model cardsource
SGLang
Serving engine
Linuxnamed in the official model cardsource

Only tools with a public source are listed: an official build (ggml-org, lmstudio-community, mlx-community, bartowski or Unsloth on Hugging Face), the model card, ollama.com or the tool's own README. Apps built on llama.cpp, such as Jan and PocketPal AI, can usually load the same GGUF files. All local apps.

Try other settings

Estimated memory needed80.6 GB
Weights 76.5 GBKV cache at 32K 0.8 GBRuntime overhead 3.3 GB

Hybrid model: only the full-attention layers keep a growing KV cache; linear/conv layers keep a small fixed state (not counted).

21 hardware options fit

Cheapest real offer per device from AI Hardware Deals, converted to EUR at approximate rates. Multi-GPU rows multiply the card price.

SetupHeadroom
Framework Desktop (Ryzen AI Max+ 395, 128GB)
unified memory
1 device120 GB39.4 GB€2,875
used, ebay.co.uk
≤ 42 tok/s
GMKtec EVO-X2 (Ryzen AI Max+ 395, 128GB)
unified memory
1 device120 GB39.4 GB€3,175
new, newegg.com
≤ 42 tok/s
ASUS Ascent GX10 (GB10, 128GB)
unified memory
1 device120 GB39.4 GB€4,136
new, alternate.de
≤ 45 tok/s
HP Z2 Mini G1a (Ryzen AI Max+ PRO 395, 128GB)
unified memory
1 device120 GB39.4 GB€5,686
new, mindfactory.de
≤ 42 tok/s
Lenovo ThinkStation PGX (GB10, 128GB)
unified memory
1 device120 GB39.4 GB€5,829
new, karley.de
≤ 45 tok/s
Apple Mac Studio M4 Max 128GB (2025)
unified memory
1 device96.0 GB15.4 GB€5,979
used, ebay.co.uk
≤ 89 tok/s
Apple Mac Studio M5 Max 128GB (2026)
unified memory
1 device96.0 GB15.4 GB€6,189
new, macconsultshop.de
≤ 100 tok/s
Dell Pro Max with GB10 (FCM1253, 128GB)
unified memory
1 device120 GB39.4 GB€6,663
new, eurieka.ie, excl. VAT
≤ 45 tok/s
Apple Mac Studio M3 Ultra 256GB (2025)
unified memory
1 device192 GB111 GB€6,724
used, apple.com
≤ 134 tok/s
Gigabyte AI TOP ATOM (GB10, 128GB)
unified memory
1 device120 GB39.4 GB€6,795
new, grafikkarten.com
≤ 45 tok/s
NVIDIA DGX Spark (GB10, 128GB)
unified memory
1 device120 GB39.4 GB€6,999
new, grafikkarten.com
≤ 45 tok/s
HP ZGX Nano G1n AI Station (GB10, 128GB)
unified memory
1 device120 GB39.4 GB€7,127
new, office-partner.de
≤ 45 tok/s
MSI EdgeXpert MS-C931 (GB10, 128GB)
unified memory
1 device120 GB39.4 GB€7,308
new, buyzero.de
≤ 45 tok/s
NVIDIA A40 48GB
server GPU (passive cooling)
2× cards94.0 GB13.4 GB€8,509
used, ebay.co.uk
n/a
NVIDIA RTX A6000 48GB
workstation GPU
2× cards94.0 GB13.4 GB€8,698
used, ebay.ca
n/a
Apple Mac Studio M5 Ultra 256GB (2026)
unified memory
1 device192 GB111 GB€9,830
new, abt.com
≤ 196 tok/s
NVIDIA RTX 6000 Ada 48GB
workstation GPU
2× cards94.0 GB13.4 GB€18,786
new, jacob.de
n/a
NVIDIA A100 80GB PCIe
server GPU (passive cooling)
2× cards158 GB77.4 GB€29,998
used, ebay.nl
n/a
NVIDIA DGX Station (GB300)
unified memory
1 device740 GB659 GB€83,738
new, configurator.exxactcorp.com
≤ 1161 tok/s
AMD Radeon Pro W7900 48GB
workstation GPU
2× cards94.0 GB13.4 GBno verified pricen/a
Apple Mac Studio M5 Ultra 512GB (2026)
unified memory
1 device384 GB303 GBno verified price≤ 196 tok/s

Speed ceiling is memory bandwidth divided by the bytes of (active) weights read per token, shown only where we have a sourced bandwidth figure. Real decode speed is lower, especially with long contexts or when splitting across cards. All memory numbers are estimates; see the methodology.

FAQ

How much VRAM does Qwen3.5 122B-A10B need?
About 80.6 GB at Q4_K_M with a 32K-token context (76.5 GB weights, 0.8 GB KV cache, 3.3 GB overhead). These are estimates.
Can I run Qwen3.5 122B-A10B on a single GPU?
Not at Q4_K_M with 32K context on any single GPU in our catalog. Use several GPUs, a high-memory unified-memory machine, a smaller quantization or a shorter context.
Which apps can run Qwen3.5 122B-A10B locally?
Verified so far: Ollama, LM Studio, llama.cpp, MLX (mlx-lm), KTransformers, vLLM, SGLang. Each entry links to its source on this page.